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The Most Studied Pathways, being the most extensively researched and containing a larger number of identified pathway genes, along with Gene-Associated Pathways, which are closely related to AD pathology-associated genes and often focused on drug development, are both more likely to yield natural products with multiple gene targets

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Molecules , 19(11), 1906619077

Nrf2 is integral to cellular defenses against oxidative damage

[2] Second, in cultured dermal microvascular and fibroblast models, GHK-Cu exposure has been associated with increased vascular endothelial growth factor expression, a change that could enhance perifollicular microcirculation