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Interestingly, phase separation is an important mechanism for maintaining the formation of protein aggregates, and TREM-1 harbours a wide range of IDRs, which are widely known as critical structures for the formation of diverse protein liquid droplets, supporting the theoretical possibility that the aggregation of TREM-1 on the cell membrane is mediated by phase separation
PMID: 26088408
Minimal side effects
Journal of Neurosurgery 89(6):971-982
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