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Description
this enzyme is impaired when the NADH: NAD + ratio increases with the reduction of FAO and lipid accumulation (Figure 1), the expression of these proteins is mainly under the control of the same group of transcription factors, namely peroxisome proliferator-activated receptors PPAR-, PPAR-/, and PPAR-
doi: 10.1054/bjoc.1999.0933
Ono Kisho
At present, immediate treatment might be recommended for patients with SMA detected during newborn screening, regardless of their SMN2 copy number
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