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Statistical significance was assumed if p -values were lower than 0.05

c , Zoom into the area of the double charged ions in the MALDI mass spectra

Briefly, the sgRNA drives Cas9 to cleave the target DNA at three nucleotides upstream of the PAM, generating DSBs that are then repaired by cell machinery based on the presence of a repair template

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The main reason is the lack of well-established, universal surface markers for plant-derived EVs reliable PDEV biomarkers and corresponding antibodies are still largely unavailable [125]