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coli induces glutaredoxin 1 and thioredoxin 2 when the bacterium is exposed to environmental hydrogen peroxide (H 2 O 2 ) (Tao, 1997

Although rupture of the plasma membrane represents the terminal event of ferroptotic death, emerging evidence indicates that ferroptotic signaling is initiated at intracellular membrane compartments, including the ER, Golgi-associated vesicles, and lysosomes 107-110

doi: 10.1371/journal.pone.0130736 38 DonovanCLiuGShenSMarshallJEKimRYAlemaoCAet al

Prolonged fluoride exposure induces spatial-memory deficit and hippocampal dysfunction by inhibiting small heat shock protein 22 in mice
