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Description
Phase 2B results for AOD9604 do not support commercial viability (obesity indication)

Besides regulating DNA methylation acting as a cofactor of the enzyme MS in the sulfur amino acid pathway, B12 also modulates different chromatin remodeling mechanisms that can affect gene expression

The B complex vitamins are integral to the synthesis of neurotransmitters and proper functioning of the central nervous system, and play a key role in the methylation and decarboxylation reactions necessary for the integrity and synthesis of DNA, proteins, phospholipids, monoamine, and catecholamine neurotransmitters [8,9,10]

Symptoms include hives, urticaria, facial swelling, and in severe cases, anaphylaxis

53(6):274 to 278
