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Gliotoxin can also lead to the reshaping of the actin cytoskeleton [54], thus contributing to cell shrinkage and filopodia disappearance, which can be reversed by Cyclic Adenosine monophosphate (cAMP) antagonist Rp-cAMP

Direct interactions of adaptor protein complexes 1 and 2 with the copper transporter ATP7A mediate its anterograde and retrograde trafficking

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Firstly, precision: potential therapeutic strategies targeting hypoxia and HIF-1 can precisely address the pathophysiological processes of hypoxia and inflammation, minimizing unintended impacts on normal immune function