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Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling
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216,217 In addition, the lung microbiome induces chronic inflammatory processes by activating Th2 and other pathways that may exacerbate asthma progression
However, xCT has been demonstrated to play contradictory roles in ferroptosis regulation in a tumor-promoting or suppressive manner, depending on changes in energy and nutrient metabolic pathways [48,57]
PMID: 110 YangBYangKChenYXiRHanJLiSet al
