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The pharmacodynamic concepts of maximum response and sensitivity determine the magnitude of the effect at a particular concentration (see E max and C 50 , Chapter 2
10.2174/1381612824666180712110447 [DOI] [PubMed] [Google Scholar] Sever, A
3,4 GLP-1RAs mimic the action of endogenous GLP-1, activating GLP-1R, thereby enhancing insulin secretion, inhibiting glucagon release, delaying gastric emptying, and reducing food intake through central appetite suppression
FDA NEWS RELEASE, FDA Approves First Interchangeable Biosimilar Insulin Product for Treatment of Diabetes
[DOI] [PubMed] [Google Scholar] 28.Brownlee M
