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doi: 10.3390/ijms22115904 259

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With the progression of ALS there may be an additional decrease in GABA concentration due to a decrease in glutamine released from the glutamate/glutamine neurotransmitter cycle being required for net GABA synthesis (Figure 1C shows the additional decrease in cellular GABA predicted with further progression of ALS

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doi:10.1016/j.freeradbiomed.2011.04.013

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Plasma insulin levels were measured via ELISA assays using an ultrasensitive mouse insulin kit (Crystal Chem)

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In this model, the PTC is thought to have been assembled in phases one and two

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