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It catalyzes the conversion of free long-chain fatty acids into acyl-CoA derivatives, facilitating their integration into cell membranes ( 2.1.4 Iron-responsive element-binding protein 2 Other molecules involved in lipid and iron metabolism also regulate ferroptosis, including iron-responsive element-binding protein 2 (IRP2) ( 2.2 Organelle-specific regulation of ferroptosis Organelle interactions are fundamental to the regulation of ferroptosis and include various cellular compartments such as mitochondria and the endoplasmic reticulum (ER), which work in conjunction with lipid metabolic pathways ( Figure 2 )

Arabidopsis 10-formyl tetrahydrofolate deformylases are essential for photorespiration

Deletion of pilE was again found critical for intracellular growth/survival and for the transcellular crossing

Role of Kallikrein 7 in body weight and fat mass regulation

Lancet Neurol (2021) 20(1):6880