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Alternatively, by substituting the arginine side chain with a lysine residue and using guanidine as a reagent, a connection between three lysines could be formed

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doi: 10.1016/0041-008X(86)90312-1

Recombinant human glucagon-like peptide-1 (rhGLP-1) reversed diabetic nephropathy by reducing oxidative stress in glomerular microvascular endothelial cells and protecting the glomerulus and tubules through inhibition of PKC and activation of PKA [120]

I.MedeirosJ