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The submucosal plexus consists of a single layer of rather small ganglia in common laboratory species (i.e., mouse, rat, and guinea pig), but in larger mammals and humans it consists of two layers of ganglia, called the inner and outer submucosal plexus [formerly Meissners plexus and Henles/Schabadaschs plexus (the exact attribution is uncertain), respectively] (4, 4446)

This makes them ideal for individuals with trouble absorbing Vitamin B12 orally, such as those with gastrointestinal issues like Crohns disease or pernicious anemia

Pain slows you down

Research-Oriented Dosage Considerations This section is strictly for laboratory guidelines and NOT for human consumption

To read more about interoception issues and neurodivergence, you can see my full article on it here