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Ferroptosis: machinery and regulation

Stem Cells 2011

Ponemah v6.x Accelerate results with flexible, powerful software

[DOI] [PubMed] [Google Scholar] 172.Rodriguez-Enriquez S., He L.H., Lemasters J.J

SIRT1 deacetylates Sterol Regulatory Element-Binding Protein-1c (SREBP-1c) and Carbohydrate Response Element-Binding Protein (ChREBP), suppressing the expression of their downstream lipogenic genes fatty acid synthase (FAS) and acetyl-CoA carboxylase 1 (ACC1), ultimately inhibiting lipogenesis and mitigating MAFLD
