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Graphical abstract Using high-throughput RNA-sequencing and proteomics techniques, we identified genes and metabolites differentially expressed during sulfur starvation in P
Sun, H., Li, Y., Kong, H., Dai, S
Funding The project was supported by the Czech Science Foundation (20-28072S), Charles University Grant Agency (343621), CePaViP provided by The European Regional Development Fund and Ministry of Education, Youth and Sports of the Czech Republic (CZ.02.1.01/0.0/0.0/16_019/0000759), the MiCoBion project funded by EU Horizon 2020 (810224), Czech-BioImaging large RI projects (LM2018129 and CZ.02.1.01/0.0/0.0/18_046/0016045, funded by MEYS CR and ERDF) , Moore-Simons Project on the Origin of the Eukaryotic Cell ( Acknowledgments Karel Harant and Pavel Talacko from the Laboratory of Mass Spectrometry, Biocev, Charles University, Faculty of Science, where the proteomics and mass spectrometric analyses were performed
Integrated analysis of these results revealed that 14 genes associated with the GSH metabolism pathway were highly expressed in the recurrence group
Meanwhile, the mechanisms of ferroptosis-related ocular diseases and the therapeutic strategies targeting ferroptosis have also been elaborated
