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The strongest data comes from Harshini Neelakantan, Stan Watowich, and colleagues at the University of Texas Medical Branch (UTMB)

Two applications per day, every day, for months and years on end

Adipocyte (Fat Cell) Function Studies : Investigating changes in fat breakdown (lipolysis) and fat storage (lipogenesis) in isolated adipose tissue or cultured fat cells, including measurement of glycerol and free fatty acid release as metabolic markers

It upregulates genes associated with trophic support and synaptic plasticity while downregulating cytokine and oxidative stress pathways

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