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Treatments targeting these age-related alterations are considered as potential approaches to prevent pathogenic deterioration and frailty (14)

Mild headaches, slight fatigue, or minor injection site irritation can occur as the body adjusts

, Transplanted articular chondrocytes co-overexpressing IGF-I and FGF-2 stimulate cartilage repair in vivo

BBR lowered pro-inflammatory cytokines (IL-1, IL-6, TNF-), mitigated HFD-induced metabolic endotoxemia, and improved obesity-related metabolic dysfunctions [36]

doi: 10.3390/nu8080513 85
