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doi: 10.1530/EJE-22-0440 65 McCormackADekkersOMPetersennSPopovicVTrouillasJRaverotGet al

Vitamin B12 is essential for sustaining healthy red blood cells and nerve cells and converting food into energy

To view a copy of this licence, visit About this article Cite this article Snelson, M., Vanuytsel, T

Miyazawa, The oxidation of 8-oxo-7,8-dihydroguanine by iodine

This model proposes that mGSH depletion due to its covalent binding to NAPQI acts as a first-hit, which is followed by a burst of mitochondrial ROS production that activates a second hit involving mitogen-activated protein kinases (MAPKs) that in turn amplifies the wave of mitochondrial ROS generation (Lemasters, 1998)