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A recent study found that inhibiting PHB2-mediated mitophagy using PHB ligands (e.g., FL3) or shPHB2 effectively blocked cancer cell proliferation, revealing that targeting PHB2-mediated mitophagy is a promising strategy for cancer therapy [321]

W., Vriend, G., Sander, C

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When norepinephrine is released from LC neurons it activates both 1 and -adrenergic receptors in subcortical regions of the brain responsible for arousal

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