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Moreover, in a study, an innovative strategy was employed to enhance the therapeutic index of interleukin-12 (IL-12) by targeting its delivery to tumors ( 2.4 Modulating cytokines in the tumor microenvironment using peptides Cytokines play pivotal roles in orchestrating immune responses and driving the progression of PCa (Mao et al., 2021)

On the other hand, a study by Lee et al

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