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In particular, the biochemical analysis revealed the accumulation of MMA and alteration of metabolites in vB12-related pathways in the brain of adult Tbx1 +/ mice, and in mice carrying a multigenic deletion ( Df1/ + ) of 22q11.2DS orthologs that includes Tbx1 (19)

TGF-1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency

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PRMT1 regulates NEDD4-mediated PPAR ubiquitination by methylating UBE2m in TECs Additionally, we explored how the PRMT1/UBE2m axis inhibits fatty acid metabolism