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The mechanisms of FA-induced insulin resistance have been intensively studied and have been attributed to two metabolites of FAs - DAGs and ceramides

The SURPASS-3 MRI substudy added another layer, showing tirzepatide actually reduced muscle fat infiltration across all doses, indicating improved muscle quality even as total muscle volume decreased

Targeted Fat Burning: MIC (Methionine, Inositol, Choline) stimulates the breakdown of fat in the liver and improves bile flow

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