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[Google Scholar] 5.Pizzorno J

It is possible that circulating IGF-II after release from the ternary complex is cleared from the circulation by binding to the IGF2R identical to the mannose-6-phosphate receptor which is associated with lysosomes and results in degradation of IGF-II in endothelial cells (23)

The reduction in glucose flux toward the TCA cycle favors rewiring to lactate production

That visibility has brought both increased interest and increased confusion, making it harder to separate established science from emerging or unsupported claims

Food Res Intern 150:110746
