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[3] Braidy N, Berg J, Clement J, Khorshidi F, Poljak A, Jayasena T, Grant R, Sachdev P

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Prior art literature such as United States Patents US4797284 and US4880633 had employed propylene glycol as a penetration enhancer which is gelled with 2 percent hydroxypropyl guar (HP-60 Jaguar from Celanese) which served as a dissolved drug reservoir

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