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Further, although spatiotemporally controlled brain-targeted drug delivery can be achieved with physical strategies, safety remains the most important concern preventing clinical translation

Sharifi-Rad J, Quispe C, Mukazhanova Z, Knut E, Turgumbayeva A, Kipchakbayeva A, Seitimova G, Mahomoodally MF, Lobine D, Koay A, Wang J, Sheridan H, Leyva-Gmez G, Prado-Audelo MLD, Cortes H, Rescigno A, Zucca P, Sytar O, Imran M, Rodrigues CF, Cruz-Martins N, Ekiert H, Kumar M, Abdull Razis AF, Sunusi U, Kamal RM, Szopa A

Investigating the preventive roles of antioxidants, assessing long-term safety, and exploring lifestyle impacts on oxidative stress are crucial areas for further study

An update on the efficacy of anti-inflammatory agents for patients with schizophrenia: a meta-analysis

Evidence Boundary Not supported by published human clinical trial data for dosing, absorption, or efficacy
