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Clinical evidence, supported by advanced imaging techniques such as susceptibility-weighted imaging (SWI) and quantitative susceptibility mapping (QSM), confirms increased iron deposition specifically within the SN of PD patients, particularly in its ventral region, correlating with symptom severity (Martin-Bastida et al., 2017

On top of the challenges in the reproducibility of results, since MSCs are allogeneic, they also have limited neuronal differentiation potential and relatively high rates of immune rejection

BPC 157 induces NO release of its own [55,56] and controls vasomotor tone through the activation of the Src-Caveolin-1-eNOS pathway [46], superseding that of L-arginine

The highly reactive NAPQI metabolite binds covalently to cell macromolecules, leading to dysfunction of enzymatic systems and structural and metabolic disarray

This is why repeating rounds of antimicrobials to kill off the bacteria and archaea may not be the best approach for everyone