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Several drugs, including colchicine, have been reported to reduce the absorption of methylcobalamin, vitamin B12

However, after consulting a trusted veterinarian, I ultimately chose not to go through with them

However, this total measurement does not always reflect the amount of B12 actually available for cellular use, which is why some patients experience deficiency symptoms despite borderline-normal results

This commonly includes lifelong treatment for pernicious anaemia, managing severe B12 deficiency with neurological symptoms to prevent further damage, and for individuals post-gastric surgery due to impaired absorption

PMID 16042604