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Description
Although the mechanism of action of auranofin is incompletely understood, some reports link it to altered regulation of p53 pathways

What animal models and community sources describe: Anti-catabolic signaling activates within hours

Pediatrics 113, e365e370

Nrf2 activation has been implicated in cancer and is associated with a poor outcome and reduced survival in tumor types such as non-small cell lung cancer (97, 98)

Van Lommel R, Bettens T, Barlow TMA, et al
