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Indeed, patients with non-small cell lung cancer (NSCLC) at stages I-III display pre-cachexia as no changes in fat and lean body mass and any activation of ubiquitin-proteasome system are observed, despite the presence of systemic inflammation and a reduction in muscle performance (Op den Kamp et al., 2012)
An LTQ Orbitrap MS interfaced to an Agilent 1200 LC was used for LCMS/MS analysis
PubMed , For your reference: For your reference: For your reference: 19 Leslie, Stephen W., et al
Park, J
This promotes ROS accumulation, which in turn generates cellular damage [130] (Fig
