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10.1093/alcalc/agq034 57 LiuJ.WangX.LiuR.LiuY.ZhangT.FuH.et al (2014)

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Nicotine's weight effects appear to result especially from the drug's stimulation of 34 nicotine acetylcholine receptors (nAChRs), which are located on pro-opiomelanocortin (POMC) neurons in the arcuate nucleus (ARC), leading to activation of the melanocortin circuit, which is associated with body weight

Likewise, another meta-analysis revealed an improved lipid profile following synbiotic administration (28)
