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Cervical spinal magnetic resonance imaging (MRI) revealed a longitudinally extensive transverse myelitis involving the dorsal medulla to C7 cord

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DOI: 10.1038/s41398-018-0297-1 23

The production of oxalate and its related metabolites can accelerate purine catabolism, thereby enhancing uric acid synthesis

These studies provided the rationale for testing cagrilintide in humans, both as a single agent and in combination with GLP-1 analogues, to harness the enhanced weight-lowering effect observed in animals