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Pharmacological Effects of Meldonium: Biochemical Mechanisms and Biomarkers of Cardiometabolic Activity

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[DOI] [PubMed] [Google Scholar] 83.Zhang L., Sui C., Yang W., Luo Q

Ran LS, Liu WH, Fang YY, et al

During ischemia, overstimulation of NMDA receptors by glutamate and glycine triggers pathological calcium influx, leading to mitochondrial calcium overload and subsequent mitochondrial permeability transition pore (mPTP) opening, further initiating apoptotic cascades [144] (Fig