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Given the pronounced sexbased variations in drug response, personalized treatment strategies have been advocated to address the fact that up to 60% of neuropathic pain patients failed to achieve adequate pain relief with standard pharmacotherapy [116]
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FGFR blockade inhibits targeted therapy-tolerant persister in basal FGFR1- and FGF2-high cancers with driver oncogenes
It is also assumed that the Mg atom in the chlorophylls tetrapyrrole ring may be replaced with a trivalent As atom, which may also impede the pathway that produces chlorophyll [220]
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