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Yet, as with NRF2, tumor contexts complicate interpretation: HO-1 is overexpressed in some cancers, including HCC, where it actively supports tumor progression by enhancing survival via mechanisms such as increasing cancer cell proliferation, conferring resistance to chemo- and radiotherapy, and promoting angiogenesis, as indicated by its strong correlation with VEGF expression and microvascular invasion

It is equally important to note that NAC use in clinical settings has not been associated with an increased risk of lung cancer

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This is because B12 is only found naturally in animal foods

Historical Background and Scientific Context Sterile water preparations have long been utilised in laboratory science and pharmaceutical research as a base solvent for compound preparation