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General Deficiency Correction and Hematologic Goals Cyanocobalamin works well for general repletion, especially in cases of dietary deficiency, gastrointestinal malabsorption, or post-surgical needs

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doi: 10.1186/s12915-020-00836-x 141 FerreiraMRMulsADearnaleyDPAndreyevHJN

Furthermore, treatment with recombinant IGF-1 enhanced erythroid colony formation in in vitro culture of bone marrow cells.126 In the same way, end-stage CKD patients undergoing hemodialysis and presenting erythrocytosis showed elevated serum IGF-1 levels, while EPO levels were variable
