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Mit speziellen Loesungsvermittlern wie Cyclodextrin wird eine therapeutische Konzentration erreicht, die mit oraler Einnahme absolut unmoeglich waere

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Rheumatoid arthritis (RA) is significantly influenced by the presence of oxidative stress, which acts as a pivotal factor in its pathogenesis

Given that the cellular thiol network, including GSH, involves crosstalk between the cytosol and organelles, we selected two of the dysregulated enzymes, which had been identified by 2D electrophoresis, with important roles in mitochondrial function, i.e., Aco2 and mitochondrial creatine kinase (mtCK) (Fig