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However, elevated serum levels of IgG4 are detected in other diseases (e.g., bronchial asthma, atopic dermatitis, pemphigus, and multicentric Castlemans disease), and has been reported to be a feature of about 10% of cases of malignancy (e.g., pancreatic cancer and cholangiocarcinoma) [15]

Recent advances in the genetics of autoimmune disease

This genetic evidence, coupled with the livers central role in systemic A clearance, emphasizes its critical function in reducing brain A burden and suggests therapeutic opportunities targeting hepatic A clearance pathways

Ann Surg 263(2):251257 Solanky D, Krishnamoorthi R, Crews N, Johnson M, Wang K, Wolfsen H et al (2019) Barrett esophagus length, nodularity, and low-grade dysplasia are predictive of progression to esophageal adenocarcinoma

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