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Resistance training specifically tells the body that muscle tissue remains necessary and should be preserved despite caloric deficit

These alterations can have profound effects on gene expression associated with dopaminergic signaling, mitochondrial function, and neuroinflammation, which are key processes implicated in complex mechanisms of these diseases (29)

10.15252/emmm.201606184 59 FujiiM.ShimokawaM.DateS.TakanoA.MatanoM.NankiK.et al (2016)

Diabetes mellitus accelerates the progression of osteoarthritis in streptozotocin-induced diabetic mice by deteriorating bone microarchitecture, bone mineral composition, and bone strength of subchondral bone

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