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This patient's imaging shows widespread dilation of the entire left renal pelvis rather than an isolated calyceal dilation

152 Dysregulation of Wnt/-catenin signalling is often caused by mutations of various components in the pathway, particularly mutations or silencing of the Wnt tumour suppressor, which occurs frequently in various cancer types, such as adenomatous polyposis coli (APC) mutations, 193 Axin1/2 mutations, 194,195 GSK3 deletions, 196 inactivation mutations of E3 ubiquitin ligase RNF43, 196 and Znrf3
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[DOI] [PubMed] [Google Scholar] 67.Jang DP, Lee JM, Lee E, Park S, Kim JJ, Namkoong K, Yoon KJ, Kim IY, Kim SI
