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This suggests that components beyond HCl, such as pepsin, bile acids and trypsin, alongside, may play significant roles in GERD pathophysiology (Reference Li, Xu and Zhou10) , in addition to factors such as low adherence to treatment and the presence of functional heartburn (Reference Mermelstein, Chait Mermelstein and Chait11)

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The term metabolism is derived from the Greek word change, which refers to a series of orderly chemical reactions for life maintenance that occur in cells, tissues or organisms

Moreover, there were no differences in TOS, TAS, and OSI values between the groups of patients suffering from migraine with and without aura [33]

However, large amounts of excess skin often do not completely resolve without surgical treatment