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A meta-analysis of glucocorticoid-induced physiological stress studies found that corticosteroids increase oxidative stress, most notably after 3 weeks of administration [53]
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Molecular docking and modeling revealed that EGCG can directly bind to TLR4, IRAK1 and caspase-3 (37)

While the contractility and the ring diameter of the ciliary body are unaffected by age [45,53], there is an age-linked reduction in forward ciliary body movement, which is compensated for by greater centripetal ciliary movement [54,55]

doi: 10.1111/ajco.13911