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Macrophage-driven pro-inflammatory and anti-inflammatory responses play a critical role in the formation and progression of kidney stones [39, 40]

doi:10.1053/gast.2003.50100Google Scholar Spirl, C, Nathanson, MH, Fiorotto, R, et al

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The main ones are Super Oxide Dismutase(SOD), Trx system and Gpx family ( The Gpx family of glutathione peroxidases is an evolutionarily highly conserved group of enzymes containing eight main isoenzymes, among which Glutathione Peroxidase 4(GPx4) utilizes GSH as a cofactor to convert lipid hydroperoxides into nontoxic lipids alcohols and reduce free radical accumulation ( Figure 3 )

Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission
