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Giustarini, D., Dalle-Donne, I., Lorenzini, S., Milzani, A
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Full Staggered Titration Schedule Recommended staggered co-titration across 24 weeks Phase Tirz initiation Weeks 1-4 Tirzepatide 2.5 mg/week Cagrilintide Not started Notes Confirm tirzepatide GI tolerance first
Lysosomes also facilitate autophagyincluding chaperone-mediated autophagy (CMA) and macroautophagydegrading damaged organelles and proteins
