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Written informed consent was obtained from all participants before entry into the study

Numbness or Tingling Sensations Vitamin B12 is important for nerve health

The methionine cycle is responsible for the synthesis of SAM and thus for the majority of all methylation reactions in the body

thus, these differences in measurement methods may not be significant to this study

Potential concerns include delayed therapeutic response onset, unclear optimal titration speed, and limited head-to-head efficacy data versus standard dosing
