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doi: 10.1080/01616412.2019.1710416 143 MengFLiNLiDSongBLiL

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Notably, mitochondrial dysfunction induces endoplasmic reticulum (ER) stress, excessive reactive oxygen species (ROS) production, aberrant autophagy, apoptosis, and disrupted calcium ion homeostasis, culminating in inflammatory imbalance via activated signaling cascades [13,14,15,16,17]