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Choline, inositol, and methionine are studied for their roles in hepatic phosphatidylcholine production (required for VLDL export of fat from the liver), methylation cycle function, and one-carbon metabolism pathways central to NAFLD and metabolic syndrome research

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B Vitamins Can Reduce Body Weight Gain by Increasing Metabolism-related Enzyme Activities in Rats Fed on a High-Fat Diet Supplementation with B vitamins could effectively reduce BW gain and plasma levels of lipids by improving energy metabolism-related enzyme activities in rats, thus possibly providing potential benefits to humans