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Most recently, a self-assembled pH-sensitive superparamagnetic iron oxide nanoclusters (SPIONCs) is reported to enhance in situ ferroptosis and apoptosis of lung tumors with radiotherapy and chemodynamic therapy via releasing iron in the tumor microenvironment (TME) [118]
Normal cellular metabolism, especially energy production in the mitochondria, naturally produces toxic byproducts like hydrogen peroxide and lipid peroxides
Chen P, Chen Z, Zhai J, Yang W, Wei H
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