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Some pharmacological agents that have shown promising applications, include dopamine agonist like apomorphine and ropinirole, and catechol-O-methyltransferase (COMT
In a large meta-analysis of 41 randomized controlled trials including 2,768 patients with systemic inflammatory response syndrome or sepsis, late application (more than 24 hours after the onset of symptoms) of N-acetylcysteine was associated with cardiovascular instability (31)
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doi: 10.1016/S0014-5793(01)02222-0
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