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In parallel, the discovery of a fundamentally novel T helper cell population, T helper 17 (Th17) cells, in addition to a unique highly specialized subtype, Th17.1 cells, capable of producing both Th1 and Th17 cytokines, including IFN and IL-17A, suggested that sarcoidosis might be autoimmune in nature (137, 138)

Likewise, a negative correlation, as found between GSH production and cystine, denotes that a lower flux rate through the exchange reaction of the metabolitemore uptake or less secretionenables the model to produce GSH more rapidly

FSP 1 shuttles the reducing equivalents from NADPH to the lipid bilayer, allowing CoQ 10 to interconvert with CoQ 10 H 2 , thereby inhibiting lipid peroxidation and maintaining the effective concentration of CoQ 10 H 2

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Glutathione is the final end-stage product