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Nyhan, L

Importantly, hepatic gluconeogenesis produces glucose-6-phosphate, which together with that produced from glycogen degradation (glycogenolysis) must be hydrolyzed by glucose-6-phosphatase in the endoplasmic reticulum to be released as glucose into the circulation (Cahill et al., 1959)

Therefore, the pRNA/siMT2A chimera represents a highly potent therapeutic approach against cancer

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